Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877985 | 0.84 | FFAR1 (0.57) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11212940 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7224442 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11876632 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11218179 | 0.80 | HSP90AA1 (0.57) | SMN1; SMN2MAPTALDH1A1PLA2G1BATG4B | |
| SCHEMBL7916730 | 0.79 | ALDH1A1 (0.48) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL5288477 | 0.78 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8030765 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1532181 | 0.77 | TSHR (0.59) | SMN1; SMN2MAPTALDH1A1TSHRKMT2A | |
| SCHEMBL9787226 | 0.77 | MAPT (0.64) | SMN1; SMN2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |