SCHEMBL528948

SCHEMBL528948

CCOC(=O)C(=CC1CCCCC1)CC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.41
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP2D6 P10635 1/20 0.39
GRIK2 Q13002 1/20 0.39
THRB P10828 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 2/20 0.35
GAA P10253 2/20 0.34
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7046851 1.00 GRIK1 (0.41) GRIK1ALDH1A1SMN1; SMN2CYP2D6GRIK2
SCHEMBL4661636 0.88 GAA (0.42) GRIK1ALDH1A1SMN1; SMN2CYP2D6GRIK2
SCHEMBL1405605 0.85 GRIK1 (0.44) GRIK1ALDH1A1SMN1; SMN2GRIK2EGLN1
SCHEMBL29117853 0.85 GRIK1 (0.41) GRIK1ALDH1A1GRIK2THRBATM
SCHEMBL1405604 0.85 GRIK1 (0.44) GRIK1ALDH1A1SMN1; SMN2GRIK2EGLN1
SCHEMBL528603 0.83 GRIK1 (0.42) GRIK1ALDH1A1GRIK2EGLN1NPSR1
SCHEMBL15913551 0.78 NPSR1 (0.46) GRIK1ALDH1A1SMN1; SMN2CYP2D6THRB
SCHEMBL165975 0.78 GRIK1 (0.57) GRIK1ALDH1A1SMN1; SMN2GRIK2KDM4E
SCHEMBL1088357 0.78 GRIK1 (0.57) GRIK1ALDH1A1SMN1; SMN2GRIK2KDM4E
SCHEMBL22993864 0.77 GLO1 (0.40) GRIK1ALDH1A1THRBATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4112676-B1 METHOD FOR PRODUCING NITRILE RUBBER ZEON CORP (JP) 2026-02-18 EP disclosed
EP-3904430-B1 METHOD FOR RECYCLING NITRILE RUBBER ZEON CORP (JP) 2025-12-03 EP disclosed
EP-3916021-B1 METHOD FOR PRODUCING CARBOXYL GROUP-CONTAINING LIQUID NITRILE RUBBER ZEON CORP (JP) 2025-11-26 EP disclosed
US-12404350-B2 Method for producing nitrile rubber ZEON CORPORATION (JP) 2025-09-02 US disclosed
US-12351716-B2 Method for recycling nitrile rubber ZEON CORPORATION (JP) 2025-07-08 US disclosed
US-12331197-B2 Power transmission belt DAYCO EUROPE S.R.L. (IT) 2025-06-17 US disclosed
EP-3404056-B1 METHOD FOR PRODUCING THERMOPLASTIC ELASTOMER COMPOSITION ZEON CORP (JP) 2025-06-11 EP disclosed
US-12202923-B2 Nitrile-group-containing copolymer rubber ZEON CORPORATION (JP) 2025-01-21 US disclosed
US-12110348-B2 Carboxyl group-containing nitrile rubber ZEON CORPORATION (JP) 2024-10-08 US disclosed
EP-3898707-B1 PROCESS FOR PRODUCING PEG ACRYLATE-HNBR COPOLYMER ARLANXEO DEUTSCHLAND GMBH (DE) 2024-09-18 EP disclosed
WO-2011117194-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2011-09-29 WO disclosed
EP-2368916-A1 Process for the production of water and solvent-free nitrile rubbers LANXESS International SA (CH) 2011-09-28 EP disclosed
EP-2009050-B1 CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT ZEON CORP (JP) 2011-08-31 EP disclosed
US-20110190441-A1 NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2011-08-04 US disclosed
US-20090186977-A1 Cross-Linkable Nitrile Rubber Composition and Cross-Linked Rubber ZEON CORPORATION (JP) 2009-07-23 US disclosed
EP-2009050-A1 CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER PRODUCT ZEON CORPORATION (JP) 2008-12-31 EP disclosed
EP-1042270-B1 ASYMMETRIC HYDROGENATION CHIROTECH TECHNOLOGY LTD (GB) 2003-04-09 EP disclosed
US-6207853-B1 SUCCINIC ACID DERIVATIVE CHIROTECH TECHNOLOGY, INC. (GB) 2001-03-27 US disclosed
EP-1042270-A1 ASYMMETRIC HYDROGENATION Chirotech Technology Limited (GB) 2000-10-11 EP disclosed
WO-1999031041-A1 ASYMMETRIC HYDROGENATION CHIROTECH TECHNOLOGY LIMITED (GB) 1999-06-24 WO disclosed