Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405605 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2NPSR1EPHX2ALDH1A1 | |
| SCHEMBL528603 | 0.98 | GRIK1 (0.42) | GRIK1GRIK2NPSR1EPHX2ALDH1A1 | |
| SCHEMBL7046851 | 0.85 | GRIK1 (0.41) | GRIK1GRIK2NPSR1ALDH1A1EGLN1 | |
| SCHEMBL528948 | 0.85 | GRIK1 (0.41) | GRIK1GRIK2NPSR1ALDH1A1EGLN1 | |
| SCHEMBL12639567 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX2ALDH1A1 | |
| SCHEMBL29117806 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX2ALDH1A1 | |
| SCHEMBL27549573 | 0.84 | GRIK1 (0.41) | GRIK1GRIK2NPSR1EPHX2ALDH1A1 | |
| SCHEMBL17073954 | 0.84 | GRIK1 (0.39) | GRIK1GRIK2NPSR1EPHX2TSHR | |
| SCHEMBL165975 | 0.82 | GRIK1 (0.57) | GRIK1GRIK2EPHX2ALDH1A1EPHX1 | |
| SCHEMBL1088357 | 0.82 | GRIK1 (0.57) | GRIK1GRIK2EPHX2ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975170-B9 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-11-02 | — | — | EP | disclosed |
| EP-1975170-B9 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-11-02 | — | — | EP | disclosed |
| US-7935841-B2 | Bisphospholanes for use as catalysts in asymmetric reactions | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-03 | — | — | US | disclosed |
| US-7935841-B2 | Bisphospholanes for use as catalysts in asymmetric reactions | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-03 | — | — | US | disclosed |
| EP-1975170-B1 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-03-09 | — | — | EP | disclosed |
| EP-1975170-B1 | Bisphosphine ligands for asymmetric syntheses | DAIICHI FINE CHEM CO LTD (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-7569730-B2 | Bisphosphine ligand | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569730-B2 | Bisphosphine ligand | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569730-B2 | Bisphosphine ligand | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | JACKSON PHILIP M | 2009-04-16 | — | — | US | disclosed |
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | JACKSON PHILIP M | 2009-04-16 | — | — | US | disclosed |
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | DAIICHI FINE CHEMICAL CO., LTD. (JP) | 2008-10-02 | — | — | US | disclosed |
| EP-1975170-A1 | Bisphosphine ligands for asymmetric syntheses | Daiichi Fine Chemical Co., Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1975170-A1 | Bisphosphine ligands for asymmetric syntheses | Daiichi Fine Chemical Co., Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099358-A1 | BISPHOSPHOLANES FOR USE AS CATALYSTS IN ASYMMETRIC REACTIONS | BPGM, PFKFB3, PFKFB4 | GRIK1 1098/4885GRIK2 786/4885NPSR1 627/4885 |
| US-20080242534-A1 | NOVEL BISPHOSPHINE LIGAND | GPR4, HRH4, GPR3 | GRIK1 1289/4885GRIK2 2509/4885NPSR1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.