SCHEMBL4661636

SCHEMBL4661636

CCOC(=O)CC(=CC1CCCCC1)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
GRIK1 P39086 2/20 0.38
THRB P10828 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 4/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GRIK2 Q13002 1/20 0.36
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528948 0.88 GRIK1 (0.41) GAAGRIK1THRBATML3MBTL1
SCHEMBL7046851 0.88 GRIK1 (0.41) GAAGRIK1THRBATML3MBTL1
SCHEMBL29117853 0.85 GRIK1 (0.41) GAAGRIK1THRBATML3MBTL1
SCHEMBL15913551 0.78 NPSR1 (0.46) GAAGRIK1THRBATML3MBTL1
SCHEMBL22993864 0.77 GLO1 (0.40) GAAGRIK1THRBATML3MBTL1
SCHEMBL17073954 0.77 GRIK1 (0.39) GAAMGAMSIMGAM2GRIK1
SCHEMBL2987392 0.77 GLO1 (0.40) GAAGRIK1THRBATML3MBTL1
SCHEMBL29117593 0.77 GLO1 (0.40) GAAGRIK1THRBATML3MBTL1
SCHEMBL16445418 0.77 GLO1 (0.40) GAAGRIK1THRBATML3MBTL1
SCHEMBL15913663 0.76 NPSR1 (0.47) GAATHRBATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166280-B Method for producing PEG acrylate-HNBR copolymers 阿朗新科德国有限责任公司 2023-07-11 CN disclosed
US-10100132-B2 Process for the preparation of polymers containing amino groups employing a heterogeneous iron catalyst ARLANXEO DEUTSCHLAND GMBH (US) 2018-10-16 US disclosed
EP-3116915-B1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING AMINO GROUPS EMPLOYING A HETEROGENEOUS IRON CATALYST ARLANXEO DEUTSCHLAND GMBH (DE) 2018-07-18 EP disclosed
US-20170081430-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING AMINO GROUPS EMPLOYING A HETEROGENEOUS IRON CATALYST ARLANXEO DEUTSCHLAND GMBH (DE) 2017-03-23 US disclosed
EP-3116915-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING AMINO GROUPS EMPLOYING A HETEROGENEOUS IRON CATALYST ARLANXEO Deutschland GmbH (DE) 2017-01-18 EP disclosed
EP-3116916-A2 PROCESS FOR THE REDUCTION OF NITRILE GROUPS OF HYDROGENATED NITRILE RUBBER Lanxess Deutschland GmbH (DE) 2017-01-18 EP disclosed
EP-1392638-B1 PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS BASELL POLIOLEFINE ITALIA SRL (IT) 2016-12-14 EP disclosed
WO-2015135863-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING AMINO GROUPS EMPLOYING A HETEROGENEOUS IRON CATALYST LANXESS DEUTSCHLAND GMBH (DE) 2015-09-17 WO disclosed
EP-2918611-A1 Process for the reduction of nitrile groups of hydrogenated nitrile rubber LANXESS Deutschland GmbH (DE) 2015-09-16 EP disclosed
EP-2918610-A1 Process for the preparation of polymers containing amino groups employing a heterogeneous iron catalyst LANXESS Deutschland GmbH (DE) 2015-09-16 EP disclosed
US-20050113599-A1 Process for preparing alkylidene-substituted -1, 4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-05-26 US disclosed
EP-1527040-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES Basel Poliolefine Italia SpA (IT) 2005-05-04 EP disclosed
EP-1527039-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES Basell Poliolefine Italia S.P.A. (IT) 2005-05-04 EP disclosed
US-20050080290-A1 Process for preparing alkylidene-substituted-1, 4-dions derivatives BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-04-14 US disclosed
CN-1512979-A Process for preparing alkylidene substituted succinic acid esters ��������ϩ����������޹�˾ 2004-07-14 CN disclosed
EP-1392638-A1 PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS Basell Poliolefine Italia S.p.A. (IT) 2004-03-03 EP disclosed
WO-2004014838-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-02-19 WO disclosed
WO-2004014839-A1 PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES BASEL POLIOLEFINE ITALIA S.P.A. (IT) 2004-02-19 WO disclosed
US-20030181743-A1 Process for preparing alkylidene substituted succinic acid esters BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-09-25 US disclosed
WO-2002098837-A1 PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS BASELL POLIOLEFINE ITALIA S.P.A (IT) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050113599-A1 Process for preparing alkylidene-substituted -1, 4-dions derivatives KCNJ4, NR3C2, NR4A2 GAA 4586/4885MGAM 3919/4885SI 3511/4885
US-20030181743-A1 Process for preparing alkylidene substituted succinic acid esters OGDH, SCO2, SUCNR1 GAA 3356/4885MGAM 776/4885SI 32/4885
US-20050080290-A1 Process for preparing alkylidene-substituted-1, 4-dions derivatives RTN4, NR4A2, NR3C2 GAA 4844/4885MGAM 4851/4885SI 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.