Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96857 | 0.87 | AADAT (0.48) | AADATCYP19A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL98343 | 0.85 | HTR5A (0.50) | HTR5ACYP19A1CYP11B1CYP11B2HTR2C | |
| SCHEMBL8999207 | 0.73 | GAA (0.47) | AADATHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL1317350 | 0.72 | AHR (0.56) | HTR5AHTR2C | |
| SCHEMBL18513671 | 0.70 | NPC1 (0.40) | HTR5ACYP19A1CYP11B1CYP11B2NPC1 | |
| SCHEMBL31448552 | 0.70 | SRD5A1 (0.42) | PTK2TRIM24SRD5A1MAP2K1 | |
| SCHEMBL12090742 | 0.70 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2DRD2NPC1 | |
| SCHEMBL31448535 | 0.69 | RHEB (0.43) | PTK2DRD2SRD5A1 | |
| SCHEMBL31448498 | 0.67 | NPC1 (0.46) | NPC1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL8555101 | 0.67 | SRD5A1 (0.46) | AADATCYP19A1CYP11B1CYP11B2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |