Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 5/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301397 | 0.80 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTGRIA1GRIA2 | |
| SCHEMBL725456 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTGRM8GRM4 | |
| SCHEMBL27628887 | 0.78 | MAPT (0.38) | ALDH1A1POLBMAPTKDM4EKMT2A | |
| SCHEMBL2930014 | 0.77 | BRD4 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL7632015 | 0.75 | GRM8 (0.36) | ALDH1A1POLBMAPTGRIA1GRIA2 | |
| SCHEMBL2603746 | 0.72 | POLB (0.40) | ALDH1A1POLBMAPTKDM4ECYP3A4 | |
| SCHEMBL16632477 | 0.71 | TSHR (0.45) | ALDH1A1POLBMAPTCYP1A2KDM4E | |
| SCHEMBL5282402 | 0.70 | GRIA1 (0.51) | ALDH1A1MAPTGRIA1GRIA2GRIA4 | |
| SCHEMBL2976953 | 0.70 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTKDM4EMAP2K1 | |
| SCHEMBL27989702 | 0.69 | BRD4 (0.32) | ALDH1A1POLBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002469-A2 | THERAPEUTIC COMPOSITIONS AND METHODS USING TRANSFORMING GROWTH FACTOR-BETA MIMICS | BHATNAGAR RAJENDRA S (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007002594-A1 | COSMETIC COMPOSITIONS AND METHODS USING TRANSFORMING GROWTH FACTOR-BETA MIMICS | BHATNAGAR RAJENDRA S (US) | 2007-01-04 | — | — | WO | disclosed |