SCHEMBL529067

SCHEMBL529067

C=CC(=O)NCc1ccc(C(=O)OC)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.61
LOXL2 Q9Y4K0 1/20 0.53
CA1 P00915 4/20 0.51
CA2 P00918 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
HPGD P15428 2/20 0.49
LMNA P02545 1/20 0.49
CYP4A11 Q02928 2/20 0.49
ALDH1A1 P00352 3/20 0.48
CYP4F2 P78329 1/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20763051 0.84 TGM2 (0.58) TGM2SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL732934 0.84 TGM2 (0.81) TGM2KMT2AMEN1LMNAALDH1A1
SCHEMBL12230798 0.84 TGM2 (0.54) TGM2SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL4743993 0.82 TGM2 (0.63) TGM2SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL890926 0.81 TGM2 (0.67) TGM2KMT2AMEN1ALDH1A1
SCHEMBL5357067 0.80 KMT2A (0.68) LOXL2CA1CA2SMN1; SMN2KMT2A
SCHEMBL959540 0.80 TGM2 (0.69) TGM2SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL23316960 0.78 LOXL2 (0.58) LOXL2CA1CA2SMN1; SMN2KMT2A
SCHEMBL13920455 0.78 LOXL2 (0.58) LOXL2CA1CA2SMN1; SMN2KMT2A
SCHEMBL22253411 0.78 LOXL2 (0.62) LOXL2CA1CA2SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2572243-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2021-04-07 EP disclosed
EP-3414230-B1 TETRAZOLE DERIVATIVES AS CYTOCHROME P450 INHIBITORS C26 BIOSCIENCE AB (SE) 2020-05-06 EP disclosed
US-10577333-B2 Tetrazole derivatives as cytochrome P450 inhibitors C26 BIOSCIENCE AB (SE) 2020-03-03 US disclosed
US-20190293641-A1 ASSAY IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) 2019-09-26 US disclosed
EP-2568339-B1 Lithographic printing plate precursor and method of manufacturing lithographic printing plate FUJIFILM CORP (JP) 2019-05-08 EP disclosed
EP-2598946-B1 POLYMERIZABLE COMPOSITION FUJIFILM CORP (JP) 2019-04-03 EP disclosed
US-20190040020-A1 TETRAZOLE DERIVATIVES AS CYTOCHROME P450 INHIBITORS C26 BIOSCIENCE AB (SE) 2019-02-07 US disclosed
US-20180321586-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE, AND ORGANIC-INORGANIC HYBRID PARTICLE FUJIFILM CORPORATION (JP) 2018-11-08 US disclosed
EP-2555054-B1 METHOD FOR MANUFACTURING A LITHOGRAPHIC PRINTING PLATE AND PRINTING METHOD FUJIFILM CORP (JP) 2018-06-20 EP disclosed
EP-3330096-A1 PLANOGRAPHIC PRINTING PLATE ORIGINAL, PLANOGRAPHIC PRINTING PLATE MANUFACTURING METHOD, AND ORGANIC-INORGANIC HYBRID PARTICLES FUJIFILM Corporation (JP) 2018-06-06 EP disclosed
US-20120068292-A1 POLYMERIZABLE COMPOSITION, AND PHOTOSENSITIVE LAYER, PERMANENT PATTERN, WAFER-LEVEL LENS, SOLID-STATE IMAGING DEVICE AND PATTERN FORMING METHOD EACH USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-03-22 US disclosed
WO-2012015076-A1 POLYMERIZABLE COMPOSITION FUJIFILM CORPORATION (JP) 2012-02-02 WO disclosed
WO-2011145742-A1 POLYMERIZABLE COMPOSITION FUJIFILM CORPORATION (JP) 2011-11-24 WO disclosed
EP-2378361-A1 Method for preparing lithographic printing plate Fujifilm Corporation (JP) 2011-10-19 EP disclosed
EP-2367056-A2 Method of preparing lithographic printing plate Fujifilm Corporation (JP) 2011-09-21 EP disclosed
EP-2354851-A2 Lithographic printing plate precursor and method of preparing lithographic printing plate Fujifilm Corporation (JP) 2011-08-10 EP disclosed
US-20110159437-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-06-30 US disclosed
EP-2339405-A1 Method of preparing lithographic printing plate Fujifilm Corporation (JP) 2011-06-29 EP disclosed
EP-2339401-A1 Method of preparing lithographic printing plate Fujifilm Corporation (JP) 2011-06-29 EP disclosed
EP-2339402-A1 Lithographic printing plate precursor and method of preparing lithographic printing plate Fujifilm Corporation (JP) 2011-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040020-A1 TETRAZOLE DERIVATIVES AS CYTOCHROME P450 INHIBITORS CYP1A2, CYP2E1, CYP1A1 TGM2 721/4885LOXL2 1762/4885CA1 3700/4885
US-10577333-B2 Tetrazole derivatives as cytochrome P450 inhibitors CYP1A2, CYP2E1, CYP1A1 TGM2 721/4885LOXL2 1762/4885CA1 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.