Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528262 | 0.89 | MAPT (0.42) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL528702 | 0.89 | MAPT (0.58) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL528251 | 0.87 | MAPT (0.41) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL529051 | 0.86 | MAPT (0.71) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL529639 | 0.86 | MAPT (0.55) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL528969 | 0.85 | MAPT (0.60) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL529003 | 0.85 | MAPT (0.66) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL529284 | 0.84 | ALDH1A1 (0.56) | MAPTLMNAALDH1A1KDM4EHTT | |
| SCHEMBL527969 | 0.84 | MAPT (0.60) | MAPTLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL528041 | 0.83 | HTT (0.56) | MAPTLMNAALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |