Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528251 | 0.89 | MAPT (0.41) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL529151 | 0.89 | MAPT (0.52) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL528340 | 0.88 | FFAR1 (0.51) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL529397 | 0.85 | MAPT (0.57) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL528672 | 0.85 | SMO (0.46) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL528514 | 0.84 | L3MBTL1 (0.49) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL528087 | 0.83 | KMT2A (0.55) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL529245 | 0.83 | MEN1 (0.52) | MAPTALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL529561 | 0.83 | SMN1; SMN2 (0.48) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL529028 | 0.82 | MEN1 (0.50) | MAPTALDH1A1HPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |