SCHEMBL5293554

SCHEMBL5293554

CCCCS(=O)(=O)Nc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
LMNA P02545 2/20 0.59
AR P10275 1/20 0.58
THRA P10827 1/20 0.52
AURKA O14965 1/20 0.51
KDR P35968 1/20 0.51
AURKB Q96GD4 1/20 0.51
ADRB2 P07550 1/20 0.51
ADRB1 P08588 1/20 0.51
ADRB3 P13945 1/20 0.51
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
MAPK1 P28482 1/20 0.49
KMT2A Q03164 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
NAMPT P43490 1/20 0.47
BRD4 O60885 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925053 0.95 THRA (0.58) HPGDLMNAARTHRAAURKA
SCHEMBL8756666 0.93 LMNA (0.57) HPGDLMNAARTHRAAURKA
SCHEMBL7173254 0.93 LMNA (0.57) HPGDLMNAARTHRAAURKA
SCHEMBL10886886 0.93 LMNA (0.57) HPGDLMNAARTHRAAURKA
SCHEMBL8361838 0.93 LMNA (0.57) HPGDLMNAARTHRAAURKA
SCHEMBL8364601 0.93 LMNA (0.57) HPGDLMNAARTHRAAURKA
SCHEMBL8757473 0.89 SGK1 (0.54) HPGDLMNAARTHRAADRB2
SCHEMBL8391458 0.85 LMNA (0.50) HPGDLMNAARTHRAAURKA
SCHEMBL9156206 0.84 HPGD (0.60) HPGDLMNAARTHRAAURKA
SCHEMBL10192137 0.84 HPGD (0.60) HPGDLMNAARTHRAAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2145560-A None JP disclosed
WO-2007014273-A2 SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-02-01 WO disclosed
US-20070021495-A1 SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-01-25 US disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
US-6579829-B2 Aromatic sulfonamide compound MITSUI CHEMICALS, INC. (JP) 2003-06-17 US disclosed
US-20010036903-A1 Developer composition and heat sensitive recording material MITSUI CHEMICALS, INC. (JP) 2001-11-01 US disclosed
EP-1138517-A2 Developer composition and heat sensitive recording material Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
EP-0686873-B1 Color photographic element containing new epoxy scavengers for residual magenta coupler EASTMAN KODAK CO (US) 2000-04-19 EP disclosed
US-5543276-A DISCOLORATION INHIBITION EASTMAN KODAK COMPANY (US) 1996-08-06 US disclosed
EP-0686873-A1 Color photographic element containing new epoxy scavengers for residual magenta coupler EASTMAN KODAK COMPANY (US) 1995-12-13 EP disclosed
US-4609619-A CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-09-02 US disclosed
US-4600688-A MAGENTA COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-07-15 US disclosed
US-4581326-A PYRROLOTRIAZOLE MAGENTA COUPLER AND NON-COLOR FORMING PHENOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-08 US disclosed
EP-0175573-A2 Light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-03-26 EP disclosed
US-4562146-A HIGHLY DISPERSION-STABLE MAGENTA COUPLER AND PHENOLIC COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-12-31 US disclosed
EP-0164030-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed
EP-0152296-A2 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1985-08-21 EP disclosed
EP-0145342-A2 Silver halide color photographic material KONICA CORPORATION (JP) 1985-06-19 EP disclosed
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021495-A1 SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR ESR1, ESR2, GPER1 HPGD 2286/4885LMNA 3528/4885AR 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.