SCHEMBL8364601

SCHEMBL8364601

CCCCCCCCCCCCCCCCCCS(=O)(=O)Nc1ccc(O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
THRA P10827 1/20 0.57
ADRB3 P13945 2/20 0.55
ADRB2 P07550 1/20 0.55
ADRB1 P08588 1/20 0.55
HPGD P15428 2/20 0.52
AR P10275 1/20 0.52
SGK1 O00141 1/20 0.48
ESR1 P03372 3/20 0.48
KDM4E B2RXH2 2/20 0.48
ESR2 Q92731 1/20 0.48
AURKA O14965 1/20 0.46
KDR P35968 1/20 0.46
AURKB Q96GD4 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8756666 1.00 LMNA (0.57) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL8361838 1.00 LMNA (0.57) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL10886886 1.00 LMNA (0.57) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL7173254 1.00 LMNA (0.57) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL2925053 0.98 THRA (0.58) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL8757473 0.95 SGK1 (0.54) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL5293554 0.93 HPGD (0.59) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL8391458 0.91 LMNA (0.50) LMNAALDH1A1MEN1MAPTMAPK1
SCHEMBL9453329 0.85 HPGD (0.56) LMNAALDH1A1MEN1MAPTKMT2A
SCHEMBL13763467 0.85 HPGD (0.56) LMNAALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004899-A SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1999-12-21 US disclosed
US-5981429-A AN ELECTRON-DONATING COLORING COMPOUND (COLORING AGENT) AND AN ELECTRON-ACCEPTING COMPOUND (DEVELOPER), CAPABLE OF INDUCING COLOR FORMATION BY REACTING BOTH COMPOUNDS, AND EARSING THE COLOR BY CONTROLLING HEAT ENERGY RICOH COMPANY, LTD. (JP) 1999-11-09 US disclosed
US-5641724-A AN ELECTRON DONATING CHROMOPHORIC AMINOFLUORAN COMPOUND, AN ELECTRON ACCEPTING COMPOUND AS DEVELOPER IS SELECTED FROM ORGAINC PHOSPHONIC ACID COMPOUNDS, ALIPHATIC CARBOXYLIC COMPOUNDS, A PHENOL COMPOUNDS, ALSO CONTAIN GUANIDINES RICOH COMPANY, LTD. (JP) 1997-06-24 US disclosed
EP-0574879-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1997-05-02 EP disclosed
US-5395815-A Phenolic compound electron acceptor; images; contrast; stability MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-07 US disclosed
EP-0331477-B1 Organic dye thin film and organic thin film element TOSHIBA KK (JP) 1994-07-27 EP disclosed
EP-0574879-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1993-12-22 EP disclosed
US-5153680-A Optical recording media KABUSHIKI KAISHA TOSHIBA (JP) 1992-10-06 US disclosed
EP-0331477-A2 Organic dye thin film and organic thin film element KABUSHIKI KAISHA TOSHIBA (JP) 1989-09-06 EP disclosed