Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516137 | 0.82 | NPC1 (0.75) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL8569413 | 0.82 | NPC1 (0.53) | AKR1B1NPC1RAB9ALTB4RLTB4R2 | |
| SCHEMBL7374914 | 0.81 | KMT2A (0.72) | NPC1RAB9AALOX5F2KMT2A | |
| SCHEMBL4421574 | 0.80 | NPC1 (0.66) | AKR1B1NPC1RAB9ALTB4RLTB4R2 | |
| SCHEMBL339507 | 0.79 | CES2 (0.56) | AKR1B1NPC1RAB9ALTB4RLTB4R2 | |
| SCHEMBL9122526 | 0.79 | LTB4R (0.56) | NPC1RAB9ALTB4RLTB4R2CHRM2 | |
| SCHEMBL14415480 | 0.79 | LTB4R (0.56) | NPC1RAB9ALTB4RLTB4R2CHRM2 | |
| SCHEMBL15775863 | 0.78 | AKR1B1 (0.56) | AKR1B1ALOX5CES2CES1KMT2A | |
| SCHEMBL7750313 | 0.78 | CHRM2 (0.57) | AKR1B1NPC1RAB9ALTB4RLTB4R2 | |
| SCHEMBL5144362 | 0.78 | LTB4R (0.55) | NPC1RAB9ALTB4RLTB4R2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | AKR1B1 4248/4885NPC1 4197/4885RAB9A 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.