Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.50 |
| ▸ | ABL1 | P00519 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.46 |
| ▸ | GIPR | P48546 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528857 | 0.92 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL528084 | 0.92 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL528856 | 0.90 | MAPT (0.49) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL528120 | 0.89 | LMNA (0.53) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL528399 | 0.89 | MAPT (0.56) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL528293 | 0.88 | MAPT (0.59) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL528823 | 0.86 | MAPT (0.53) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL529259 | 0.86 | MAPT (0.55) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL528511 | 0.84 | KMT2A (0.52) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL528087 | 0.84 | KMT2A (0.55) | LMNASMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |