Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528800 | 0.91 | MAPT (0.62) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL528007 | 0.91 | MAPT (0.62) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL529259 | 0.90 | MAPT (0.55) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL529579 | 0.89 | MAPT (0.61) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL529426 | 0.89 | LMNA (0.55) | MAPTLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL528511 | 0.88 | KMT2A (0.52) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL528823 | 0.88 | MAPT (0.53) | MAPTLMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL528087 | 0.88 | KMT2A (0.55) | MAPTLMNANPC1SMN1; SMN2RAB9A | |
| SCHEMBL528901 | 0.87 | MAPT (0.74) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL528937 | 0.87 | MAPT (0.47) | MAPTLMNAHTTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |