Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529259 | 0.92 | MAPT (0.55) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528307 | 0.91 | KMT2A (0.63) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528823 | 0.90 | MAPT (0.53) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528087 | 0.89 | KMT2A (0.55) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528111 | 0.89 | MAPT (0.48) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528626 | 0.89 | ALDH1A1 (0.46) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL528797 | 0.89 | MAPT (0.51) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL529002 | 0.88 | LMNA (0.50) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL528399 | 0.88 | MAPT (0.56) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL529561 | 0.87 | SMN1; SMN2 (0.48) | KMT2ALMNAMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |