Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SDHB | P21912 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603583 | 0.84 | ADORA3 (0.50) | ALDH1A1KDM4EKMT2ALMNASDHB | |
| SCHEMBL4606885 | 0.74 | CHRNA7 (0.48) | KDM4EPTGS2SMN1; SMN2 | |
| SCHEMBL12267115 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL4605302 | 0.73 | KMT2A (0.44) | KMT2ALMNASDHBPTGS2RAB9A | |
| SCHEMBL31120311 | 0.72 | CYP19A1 (0.66) | ALDH1A1KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL4606363 | 0.71 | PTGS2 (0.42) | ALDH1A1KDM4ELMNASDHBPTGS2 | |
| SCHEMBL13662645 | 0.71 | ADORA2A (0.67) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL16714717 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ALMNAGAA | |
| SCHEMBL19075476 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAGAARAB9A | |
| SCHEMBL13934198 | 0.70 | ALDH1A1 (0.42) | ALDH1A1KDM4EKMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |