Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294281 | 0.85 | HTT (0.52) | LMNASMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5806384 | 0.84 | NTRK1 (0.55) | LMNASTAT1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL14722368 | 0.80 | ALDH1A1 (0.48) | LMNASTAT1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL17453326 | 0.79 | SMN1; SMN2 (0.47) | LMNASTAT1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6422295 | 0.77 | KMT2A (0.65) | LMNASTAT1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2612161 | 0.77 | MAPK1 (0.58) | LMNASTAT1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16050054 | 0.77 | MAPK1 (0.61) | LMNASMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2824324 | 0.76 | KDM4E (0.48) | LMNASMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5111929 | 0.76 | KMT2A (0.54) | LMNAALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL2355067 | 0.76 | MAPK1 (0.56) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | LMNA 3704/4885STAT1 4289/4885SMN1; SMN2 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.