Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294292 | 0.85 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5298727 | 0.84 | ALDH1A1 (0.57) | HTTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5283603 | 0.83 | HTT (0.60) | HTTALDH1A1RECQLPOLBSMN1; SMN2 | |
| SCHEMBL5966757 | 0.82 | HTT (0.52) | HTTALDH1A1LMNARECQLPOLB | |
| SCHEMBL16112468 | 0.79 | LMNA (0.73) | HTTALDH1A1LMNARECQLPOLB | |
| SCHEMBL5323778 | 0.78 | ALDH1A1 (0.57) | HTTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5320906 | 0.78 | HTT (0.54) | HTTALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL2084437 | 0.78 | ALDH1A1 (0.56) | HTTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5285406 | 0.76 | CNR1 (0.48) | HTTALDH1A1POLBSMN1; SMN2HSD17B10 | |
| SCHEMBL26341719 | 0.73 | ALDH1A1 (0.68) | HTTALDH1A1LMNARECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | HTT 4781/4885ALDH1A1 2972/4885LMNA 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.