SCHEMBL529588

SCHEMBL529588

C/C=C/C(=O)Nc1ccccc1Nc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 1/20 0.49
▸ HTT P42858 2/20 0.48
▸ RECQL P46063 1/20 0.48
▸ MAPT P10636 5/20 0.47
▸ KDM4E B2RXH2 3/20 0.47
▸ PKM P14618 1/20 0.47
▸ MMP1 P03956 5/20 0.46
▸ MMP2 P08253 5/20 0.46
▸ MMP9 P14780 5/20 0.46
▸ EGFR P00533 5/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ ALDH1A1 P00352 3/20 0.45
▸ MAOA P21397 1/20 0.45
▸ MAOB P27338 1/20 0.45
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529589 1.00 FABP4 (0.49) FABP4HTTRECQLMAPTKDM4E
SCHEMBL19501047 0.85 KMT2A (0.55) HTTRECQLMAPTKDM4EMMP1
SCHEMBL11306733 0.85 MEN1 (0.57) HTTRECQLMAPTKDM4EPKM
SCHEMBL10938927 0.85 KDM4E (0.67) HTTRECQLMAPTKDM4EPKM
SCHEMBL262594 0.83 MAPT (0.59) HTTMAPTKDM4EMMP1MMP2
SCHEMBL262593 0.83 MAPT (0.59) HTTMAPTKDM4EMMP1MMP2
SCHEMBL4147796 0.82 MMP1 (0.63) MAPTKDM4EMMP1MMP2MMP9
SCHEMBL19142994 0.82 MMP1 (0.63) MAPTKDM4EMMP1MMP2MMP9
SCHEMBL4147799 0.82 MMP1 (0.63) MAPTKDM4EMMP1MMP2MMP9
SCHEMBL530137 0.82 MMP1 (0.70) MMP1MMP2MMP9EGFRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598825-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE Honeywell International, Inc. (US) 2013-06-05 — — EP disclosed
US-8158540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2012-04-17 — — US disclosed
WO-2012015680-A2 BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE HONEYWELL INTERNATIONAL INC. (US) 2012-02-02 — — WO disclosed
US-8080486-B1 Ballistic shield composites with enhanced fragment resistance HONEYWELL INTERNATIONAL INC. (US) 2011-12-20 — — US disclosed
US-20110143086-A1 ENVIRONMENTALLY RESISTANT BALLISTIC COMPOSITE BASED ON A NITRILE RUBBER BINDER HONEYWELL INTERNATIONAL INC. (US) 2011-06-16 — — US disclosed
US-7858540-B2 Environmentally resistant ballistic composite based on a nitrile rubber binder HONEYWELL INTERNATIONAL INC. (US) 2010-12-28 — — US disclosed
US-20090163105-A1 Environmentally Resistant Ballistic Composite Based on a Nitrile Rubber Binder SOLSTICE ADVANCED MATERIALS US, INC. 2009-06-25 — — US disclosed
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