SCHEMBL4147799

SCHEMBL4147799

CC=CC(=O)Nc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 5/20 0.63
MMP2 P08253 5/20 0.63
MMP9 P14780 5/20 0.63
MAOB P27338 3/20 0.63
EGFR P00533 2/20 0.63
MAOA P21397 1/20 0.63
TGM2 P21980 1/20 0.59
CYP1A2 P05177 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
MAPT P10636 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19142994 1.00 MMP1 (0.63) MMP1MMP2MMP9MAOBEGFR
SCHEMBL4147796 1.00 MMP1 (0.63) MMP1MMP2MMP9MAOBEGFR
SCHEMBL262594 0.93 MAPT (0.59) MMP1MMP2MMP9MAOBEGFR
SCHEMBL262593 0.93 MAPT (0.59) MMP1MMP2MMP9MAOBEGFR
SCHEMBL19501011 0.93 SMN1; SMN2 (0.61) MMP1MMP2MMP9MAOBEGFR
SCHEMBL19500988 0.88 LPAR1 (0.60) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6302452 0.87 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6302448 0.87 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL9840923 0.87 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL14543392 0.86 TGM2 (0.53) MMP1MMP2MMP9MAOBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4124145-A None JP disclosed
CN-121591654-A (2E, 4E) -5- (3, 4-dimethoxy phenyl) -N-phenyl-penta-2, 4-diene amide compound and preparation method and application thereof 苏州工学院 2026-03-03 CN disclosed
CN-120554243-A Synthesis method of beta adamantyl amide compound 南京工业大学 2025-08-29 CN disclosed
CN-118307433-A Synthesis method of beta alkylamide 南京工业大学 2024-07-09 CN disclosed
EP-4329750-A1 SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT Merck Sharp & Dohme LLC (US) 2024-03-06 EP disclosed
CN-111646917-B Preparation method of iodobenzene para-amination compound promoted by m-chloroperoxybenzoic acid 湖北工业大学 2023-04-25 CN disclosed
CN-113248396-B Preparation method of chlorobenzene para-aminated compound mediated by high-valence iodine reagent 湖北工业大学 2023-03-14 CN disclosed
CN-111960909-B Gamma-alkenyl substituted butenolide or butenolactam compound, asymmetric synthesis method thereof and ligand 河南师范大学 2023-01-24 CN disclosed
WO-2022232320-A1 SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT MERCK SHARP & DOHME CORP. (US) 2022-11-03 WO disclosed
CN-111646917-A Preparation method of iodobenzene para-aminated compound promoted by m-chloroperoxybenzoic acid 湖北工业大学 2020-09-11 CN disclosed
EP-0813525-A1 BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS BERLEX LABORATORIES, INC. (US) 1997-12-29 EP disclosed
WO-1996028427-A1 BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS BERLEX LABORATORIES, INC. (US) 1996-09-19 WO disclosed
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
JP-H04124145-A SUGAR-RESPONSIVE POLYMERIC COMPLEX MATERIAL NIPPON OIL & FATS CO LTD 1992-04-24 JP disclosed
EP-0257882-B1 N-PHENYL BUTENAMIDES WITH PHARMACEUTICAL PROPERTIES LILLY INDUSTRIES LIMITED (GB) 1991-07-24 EP disclosed
EP-0257882-A1 N-Phenyl butenamides with pharmaceutical properties LILLY INDUSTRIES LIMITED (GB) 1988-03-02 EP disclosed
US-4152324-A FOR LACQUERS, PAINTS, AND PRINTING INKS CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed
US-4077953-A Tri-dentate metal complex azo pigments CIBA-GEIGY CORPORATION (US) 1978-03-07 US disclosed
US-4045423-A MONOAZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-08-30 US disclosed
US-4045423-A MONOAZO DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-08-30 US disclosed