SCHEMBL1960031

SCHEMBL1960031

C=C(C(N)=O)C(CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C)CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2096618 0.78 MAPT (0.31) MAPTL3MBTL1
Methacrylic Acid SCHEMBL2125330 0.77 USP2 (0.38)
SCHEMBL331867 0.77 TSHR (0.38)
SCHEMBL30306612 0.76 USP2 (0.47)
SCHEMBL529602 0.76
SCHEMBL18204281 0.76 L3MBTL1 (0.33) MAPTL3MBTL1
SCHEMBL509069 0.75
SCHEMBL508665 0.75
SCHEMBL23493061 0.75 TSHR (0.38)
SCHEMBL508852 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3052534-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES Novartis AG (CH) 2016-08-10 EP claimed
WO-2015048035-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2015-04-02 WO claimed
EP-2648896-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Novartis AG (CH) 2013-10-16 EP claimed
EP-2510051-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES Novartis AG (CH) 2012-10-17 EP claimed
WO-2012078457-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2012-06-14 WO claimed
EP-2374031-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Novartis AG (CH) 2011-10-12 EP claimed
WO-2011071790-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES NOVARTIS AG (CH) 2011-06-16 WO claimed
US-20100258961-A1 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2010-10-14 US claimed
WO-2010071691-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2010-06-24 WO claimed
EP-4158392-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-04-05 EP disclosed
US-8414804-B2 Process for making ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-04-09 US disclosed
EP-2180992-A2 PROCESS FOR MAKING OPHTHALMIC LENSES Johnson and Johnson Vision Care, Inc. (US) 2010-05-05 EP disclosed
WO-2007111973-A2 PROCESS FOR MAKING OPHTHALMIC LENSES JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-10-04 WO disclosed
US-20070222094-A1 Process for making ophthalmic lenses JOHNSON & JOHNSON VISION CARE, INC. 2007-09-27 US disclosed
EP-1716436-A1 (METH) ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM Johnson and Johnson Vision Care, Inc. (US) 2006-11-02 EP disclosed
WO-2005078482-A1 (METH)ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-08-25 WO disclosed