SCHEMBL331865

SCHEMBL331865

CC=CC(=O)OCC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23493061 0.87 TSHR (0.38)
SCHEMBL35613 0.86 ATM (0.40)
SCHEMBL21050107 0.85 ALDH1A1 (0.33)
SCHEMBL19972135 0.84
SCHEMBL35420 0.84 USP2 (0.32)
SCHEMBL663826 0.83
SCHEMBL1046295 0.80 LPAR5 (0.41)
SCHEMBL996290 0.80 LPAR5 (0.37)
SCHEMBL331867 0.80 TSHR (0.38)
SCHEMBL21081955 0.79 LPAR5 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-12441845-B2 Siloxane monomer, contact lens composition and contact lens PEGAVISION CORPORATION (TW) 2025-10-14 US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
US-20240384089-A1 CONTACT LENS AND SILICONE HYDROGEL CONTACT LENS VIZIONFOCUS INC. (TW) 2024-11-21 US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
US-20240132670-A1 SILOXANE MONOMER, CONTACT LENS COMPOSITION AND CONTACT LENS PEGAVISION CORPORATION (TW) 2024-04-25 US claimed
EP-1560043-B1 Soft contact lenses JOHNSON & JOHNSON VISION CARE (US) 2008-06-18 EP claimed
US-20070229757-A1 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. 2007-10-04 US claimed
EP-1809344-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS Johnson and Johnson Vision Care, Inc. (US) 2007-07-25 EP claimed
US-7247692-B2 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-07-24 US claimed
WO-2006039467-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060074208-A1 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. 2006-04-06 US claimed
EP-1641863-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES Johnson & Johnson Vision Care, Inc. (US) 2006-04-05 EP claimed
US-20050255231-A1 Silicone hydrogels having consistent concentrations of multi-functional polysiloxanes JOHNSON & JOHNSON VISION CARE, INC. 2005-11-17 US claimed
EP-0940693-B1 Soft contact lenses JOHNSON & JOHNSON VISION CARE (US) 2005-06-22 EP claimed
WO-2005005517-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-01-20 WO claimed