Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518072 | 0.87 | POLB (0.44) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29394265 | 0.86 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1PTPN1MAOB | |
| SCHEMBL5863561 | 0.86 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1PTPN1MAOB | |
| SCHEMBL30918744 | 0.84 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5302895 | 0.83 | PTPN1 (0.39) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL31166876 | 0.81 | DHFR (0.42) | MEN1KMT2APTPN1DHFRKDM4C | |
| SCHEMBL18653599 | 0.81 | POLB (0.40) | NPC1RAB9AMEN1KMT2APTPN1 | |
| SCHEMBL14611104 | 0.81 | DHFR (0.39) | NPC1RAB9AMEN1KMT2APTPN1 | |
| SCHEMBL19352691 | 0.81 | MEN1 (0.45) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL14611091 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019930-A1 | AGENT FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007019930-A1 | AGENT FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-22 | — | — | WO | disclosed |