SCHEMBL28518072

SCHEMBL28518072

CCOc1cc(OC2CCCCO2)ccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
DHFR P00374 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CREBBP Q92793 1/20 0.36
PTPN1 P18031 2/20 0.36
LMNA P02545 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HSD11B1 P28845 1/20 0.36
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
TNK2 Q07912 1/20 0.34
ERN1 O75460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30918744 0.87 ALDH1A1 (0.40) ALDH1A1KDM4EDHFRMEN1KMT2A
SCHEMBL5296489 0.87 NPC1 (0.39) ALDH1A1DHFRMEN1KMT2APTPN1
SCHEMBL14611091 0.87 ALDH1A1 (0.46) POLBALDH1A1KDM4EMEN1KMT2A
SCHEMBL29394265 0.86 ALDH1A1 (0.54) POLBALDH1A1PTPN1NPC1RAB9A
SCHEMBL5863561 0.86 ALDH1A1 (0.54) POLBALDH1A1PTPN1NPC1RAB9A
SCHEMBL5302895 0.86 PTPN1 (0.39) POLBALDH1A1DHFRMEN1KMT2A
SCHEMBL31166876 0.84 DHFR (0.42) DHFRMEN1KMT2APTPN1KDM4C
SCHEMBL1134338 0.82 HSD11B1 (0.37) POLBALDH1A1KDM4EDHFRMEN1
SCHEMBL2065499 0.81 ALDH1A1 (0.40) POLBALDH1A1DHFRMEN1KMT2A
SCHEMBL5307835 0.81 SMN1; SMN2 (0.39) POLBALDH1A1DHFRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375168-B Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2022-03-29 CN disclosed
CN-112375168-A Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2021-02-19 CN disclosed
CN-112342032-A Rod-like polar liquid crystal molecule, preparation method thereof and rod-like polar nematic liquid crystal 华南理工大学 2021-02-09 CN disclosed