Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528370 | 0.92 | MAPT (0.52) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL529002 | 0.92 | LMNA (0.50) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL528124 | 0.92 | KMT2A (0.53) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL528374 | 0.89 | SMN1; SMN2 (0.45) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL529437 | 0.89 | MAPT (0.58) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL529259 | 0.87 | MAPT (0.55) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL528120 | 0.87 | LMNA (0.53) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL528931 | 0.85 | MAPT (0.47) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL529226 | 0.85 | SMN1; SMN2 (0.48) | MAPTNPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL528331 | 0.84 | FFAR1 (0.49) | MAPTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |