Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529757 | 0.92 | MAPT (0.53) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528370 | 0.90 | MAPT (0.52) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528124 | 0.90 | KMT2A (0.53) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528931 | 0.89 | MAPT (0.47) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528323 | 0.89 | GAA (0.44) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528307 | 0.89 | KMT2A (0.63) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528511 | 0.88 | KMT2A (0.52) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL528374 | 0.87 | SMN1; SMN2 (0.45) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL527888 | 0.87 | MAPT (0.45) | LMNAALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL528858 | 0.86 | ROCK2 (0.51) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |