Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527865 | 0.92 | SMO (0.47) | SMN1; SMN2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL529592 | 0.91 | MAPT (0.55) | SMN1; SMN2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL528660 | 0.89 | L3MBTL1 (0.48) | SMN1; SMN2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL528124 | 0.89 | KMT2A (0.53) | SMN1; SMN2HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL528251 | 0.89 | MAPT (0.41) | FFAR1SMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL528200 | 0.89 | ALDH1A1 (0.55) | FFAR1SMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL528323 | 0.88 | GAA (0.44) | SMN1; SMN2HPGDALDH1A1MAPTPOLB | |
| SCHEMBL527894 | 0.88 | RXFP1 (0.49) | SMN1; SMN2ALDH1A1MAPTPOLBCYP1A2 | |
| SCHEMBL528340 | 0.88 | FFAR1 (0.51) | FFAR1SMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL528702 | 0.86 | MAPT (0.58) | FFAR1SMN1; SMN2HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |