Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibutyl Sebacate SCHEMBL2324676 | 0.90 | TSHR (0.58) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| E1501 SCHEMBL5306129 | 0.90 | ALDH1A1 (0.53) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| Phthalic Acid SCHEMBL27652023 | 0.89 | TSHR (0.62) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| Dibutyl Sebacate SCHEMBL27647862 | 0.85 | TSHR (0.69) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| Toluic Acid SCHEMBL16020737 | 0.84 | ALDH1A1 (0.53) | TSHRALDH1A1LMNAKDM4EMEN1 | |
| Orthocresol SCHEMBL28147283 | 0.83 | DGKA (0.56) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| SCHEMBL25906609 | 0.82 | ALDH1A1 (0.66) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| Benzene SCHEMBL28221195 | 0.82 | DGKA (0.77) | DGKATSHRALDH1A1LMNAKDM4E | |
| Dibutyl Sebacate SCHEMBL7768874 | 0.82 | TSHR (0.69) | DGKATSHRALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4255174 | 0.82 | ALDH1A1 (0.79) | DGKATSHRALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | disclosed |