Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.51 |
| ▸ | WNT3A | P56704 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668303 | 0.81 | LMNA (0.65) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL29081345 | 0.81 | HPGD (0.55) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL5101292 | 0.80 | HPGD (0.69) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9047740 | 0.80 | HPGD (0.69) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL22721189 | 0.79 | ALDH1A1 (0.83) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL2516127 | 0.78 | LMNA (0.75) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27611242 | 0.78 | HPGD (0.69) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL21834838 | 0.77 | LMNA (0.54) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL3176357 | 0.76 | LMNA (0.71) | LMNAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL29351863 | 0.76 | MEN1 (0.61) | LMNAALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |