SCHEMBL668303

SCHEMBL668303

COC(=O)CCCC(=O)c1cccs1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.65
RAB9A P51151 4/20 0.65
ALDH1A1 P00352 4/20 0.65
NPC1 O15118 3/20 0.65
MEN1 O00255 1/20 0.65
POLB P06746 1/20 0.65
KMT2A Q03164 1/20 0.65
HPGD P15428 3/20 0.61
HDAC1 Q13547 1/20 0.60
CTNNB1 P35222 4/20 0.60
WNT3A P56704 4/20 0.60
TSHR P16473 2/20 0.53
PKM P14618 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MAPT P10636 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
GSK3B P49841 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5101292 0.95 HPGD (0.69) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL9047740 0.95 HPGD (0.69) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL2516127 0.90 LMNA (0.75) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL22721189 0.88 ALDH1A1 (0.83) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL1143695 0.84 ERCC5 (0.61) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL3828241 0.81 HPGD (0.63) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL3382084 0.81 HPGD (0.63) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL5300535 0.81 LMNA (0.57) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL3176357 0.81 LMNA (0.71) LMNARAB9AALDH1A1NPC1MEN1
SCHEMBL1476817 0.81 KMT2A (0.71) LMNARAB9AALDH1A1NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8945807-B2 Blends of fullerene derivatives, and uses thereof in electronic devices SOLENNE BV (NL) 2015-02-03 US disclosed
EP-2043952-B1 BLENDS OF FULLERENE DERIVATIVES AND USES THEREOF IN ELECTRONIC DEVICES SOLENNE B V I O (NL) 2014-10-29 EP disclosed
US-20130306944-A1 Blends of Fullerene Derivatives, and Uses Thereof in Electronic Devices SOLENNE BV (NL) 2013-11-21 US disclosed
US-8435713-B2 Blends of fullerene derivatives, and uses thereof in electronic devices SOLENNE BV (NL) 2013-05-07 US disclosed
US-20120043507-A1 BLENDS OF FULLERENE DERIVATIVES, AND USES THEREOF IN ELECTRONIC DEVICES SOLENNE BV (NL) 2012-02-23 US disclosed
US-20100127244-A1 Blends of Fullerene Derivatives, and Uses Thereof in Electronic Devices SOLENNE BV (NL) 2010-05-27 US disclosed
EP-2043952-A2 BLENDS OF FULLERENE DERIVATIVES, AND USES THEREOF IN ELECTRONIC DEVICES Solenne B.V. i.o. (NL) 2009-04-08 EP disclosed
WO-2008006071-A2 BLENDS OF FULLERENE DERIVATIVES, AND USES THEREOF IN ELECTRONIC DEVICES SOLENNE BV (NL) 2008-01-10 WO disclosed