Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294312 | 0.89 | HCAR2 (0.50) | HCAR2POLBRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5292551 | 0.89 | POLB (0.61) | POLBRAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL5296880 | 0.87 | HCAR2 (0.57) | HCAR2RAB9ANPC1MAPK8MAPK10 | |
| SCHEMBL5303240 | 0.84 | RAB9A (0.56) | HCAR2POLBRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5301758 | 0.79 | HCAR2 (0.52) | HCAR2HDAC1HDAC6 | |
| SCHEMBL5333224 | 0.79 | HCAR2 (0.52) | HCAR2RAB9AMEN1NPC1KMT2A | |
| SCHEMBL5293254 | 0.79 | MAPK8 (0.53) | HCAR2POLBRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14609706 | 0.79 | HCAR2 (0.53) | HCAR2RAB9ANPC1MAPK8MAPK10 | |
| SCHEMBL5303546 | 0.78 | MAPK8 (0.66) | HCAR2RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL14609517 | 0.77 | HCAR2 (0.52) | HCAR2RAB9ANPC1MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |