Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237384 | 0.73 | PDE10A (0.50) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL299951 | 0.71 | ADRA2A (0.42) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3680526 | 0.70 | ALDH1A1 (0.47) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL989154 | 0.69 | PDE10A (0.62) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL29459379 | 0.67 | PDGFRB (0.54) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL896448 | 0.66 | PDE10A (0.47) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL9704361 | 0.66 | ALDH1A1 (0.43) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL27796937 | 0.66 | PDE10A (0.42) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL9307802 | 0.66 | ALDH1A1 (0.43) | PDE10AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL13954346 | 0.66 | PDE10A (0.42) | PDE10AMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832586-A1 | Thiazole-piperidine derivatives in treatment of diseases of liver and the pancreas | Oridis Biomed Forschungs- und Entwicklungs GmbH (AT) | 2007-09-12 | — | — | EP | claimed |
| EP-1832586-A1 | Thiazole-piperidine derivatives in treatment of diseases of liver and the pancreas | Oridis Biomed Forschungs- und Entwicklungs GmbH (AT) | 2007-09-12 | — | — | EP | disclosed |