Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8910191 | 0.97 | BCAT2 (0.46) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL4560229 | 0.86 | BCAT2 (0.45) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL530130 | 0.84 | TSHR (0.45) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL4301698 | 0.82 | BCAT2 (0.41) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL27214460 | 0.82 | BCAT2 (0.63) | BCAT2KEAP1NFE2L2PARP1IKBKB | |
| SCHEMBL105262 | 0.82 | IRAK4 (0.55) | BCAT2KEAP1NFE2L2IRAK4LMNA | |
| SCHEMBL31632660 | 0.82 | IRAK4 (0.55) | BCAT2KEAP1NFE2L2IRAK4LMNA | |
| SCHEMBL27704990 | 0.81 | KEAP1 (0.57) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| Hydrochloric Acid SCHEMBL7849679 | 0.80 | IRAK4 (0.53) | BCAT2KEAP1NFE2L2IRAK4LMNA | |
| Hydrochloric Acid SCHEMBL28294057 | 0.80 | IRAK4 (0.53) | BCAT2KEAP1NFE2L2IRAK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078293-A1 | 3-N-CYCLOPROPYLMETHYL-2-FLUOROBENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMECUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036448-A1 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | GPR119, HCRTR2, MCHR1 | BCAT2 128/4885KEAP1 1063/4885NFE2L2 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.