Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301700 | 0.93 | GCGR (0.43) | BRD4BCAT2CXCR5GCGRKDM4E | |
| SCHEMBL4410163 | 0.88 | BCAT2 (0.42) | BRD4BCAT2GCGRKDM4EMEN1 | |
| SCHEMBL5480865 | 0.84 | KMT2A (0.44) | BRD4BCAT2KDM4EMEN1KMT2A | |
| SCHEMBL5479516 | 0.82 | FABP3 (0.41) | BCAT2KDM4EMEN1KMT2AFABP4 | |
| SCHEMBL4065289 | 0.80 | BCAT2 (0.43) | BRD4BCAT2GCGRKDM4EMEN1 | |
| SCHEMBL27702319 | 0.79 | NOS2 (0.41) | CXCR5KDM4EMEN1KMT2AMKNK1 | |
| SCHEMBL5803205 | 0.78 | NOS2 (0.43) | CXCR5KDM4EMEN1KMT2AMKNK1 | |
| SCHEMBL28471955 | 0.76 | BCAT2 (0.46) | BRD4BCAT2KDM4EMEN1KMT2A | |
| SCHEMBL11691857 | 0.76 | FABP4 (0.43) | KDM4EFABP4PPARGRXRANR4A2 | |
| SCHEMBL981355 | 0.76 | ESR1 (0.43) | GCGRKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |