Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530312 | 0.88 | SIRT2 (0.48) | SIRT2PTPN1SIRT1FABP4MAPT | |
| SCHEMBL530138 | 0.80 | SIRT2 (0.51) | BRD4SIRT2SIRT1BACE1FABP4 | |
| SCHEMBL28399567 | 0.76 | BACE1 (0.49) | PTPN1BACE1CA1CA2NFKB1 | |
| SCHEMBL3667411 | 0.76 | BACE1 (0.55) | PTPN1BACE1CA1CA2NFKB1 | |
| SCHEMBL27642891 | 0.76 | BACE1 (0.55) | PTPN1BACE1CA1CA2NFKB1 | |
| SCHEMBL11829602 | 0.74 | CA1 (0.55) | SIRT2SIRT1FABP4MAPTKDM4E | |
| SCHEMBL11829593 | 0.74 | CA1 (0.55) | SIRT2SIRT1FABP4MAPTKDM4E | |
| SCHEMBL28027906 | 0.73 | BRD4 (0.59) | BRD4SIRT2SIRT1FABP4MAPT | |
| SCHEMBL16586699 | 0.73 | PTGER1 (0.48) | PTPN1MAPTKDM4ENPC1MAOB | |
| SCHEMBL2328371 | 0.73 | NFKB1 (0.50) | PTPN1MAPTKDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598825-A2 | BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE | Honeywell International, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015680-A2 | BALLISTIC SHIELD COMPOSITES WITH ENHANCED FRAGMENT RESISTANCE | HONEYWELL INTERNATIONAL INC. (US) | 2012-02-02 | — | — | WO | disclosed |