SCHEMBL530141

SCHEMBL530141

CCOC(=O)Cc1ccc(I)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 1/20 0.54
MAPT P10636 2/20 0.51
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP4F2 P78329 1/20 0.47
CYP4A11 Q02928 1/20 0.47
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CFTR P13569 1/20 0.45
TBXAS1 P24557 1/20 0.45
LIPE Q05469 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PAM P19021 1/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8069266 0.95 CYP4Z1 (0.50) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL68851 0.90 CYP4Z1 (0.62) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL21572817 0.86 CYP4Z1 (0.46) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL68930 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL6057577 0.84 CYP4F2 (0.59) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL10299459 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL1107146 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL6207253 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL5545889 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL18932531 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980117-B Fenpyroximate antigen and preparation method and application thereof 西南大学 2024-07-12 CN claimed
CN-117820460-A Methoxypiperidine ethyl antigen and preparation method and application thereof 西南大学 2024-04-05 CN claimed
CN-114560834-A Spirodiclofen hapten, antigen and antibody as well as preparation method and application thereof 西南大学 2022-05-31 CN claimed
CN-113980117-A Fenpyroximate antigen and preparation method and application thereof 西南大学 2022-01-28 CN claimed
CN-112724345-B Conjugated microporous polymer, preparation method thereof and application thereof in visible light induced controllable free radical polymerization 福州大学 2021-12-21 CN claimed
CN-112724345-A Conjugated microporous polymer, preparation method thereof and application thereof in visible light induced controllable free radical polymerization 福州大学 2021-04-30 CN claimed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
WO-2025015178-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION PRETZEL THERAPEUTICS, INC. (US) 2025-01-16 WO disclosed
CN-115894447-B METTL3 inhibitors and uses thereof 成都先导药物开发股份有限公司 2024-10-01 CN disclosed
WO-2024067560-A1 SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF 中国药科大学 2024-04-04 WO disclosed
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN disclosed
CN-114560834-B Spirodiclofen hapten, antigen and antibody as well as preparation methods and applications thereof 西南大学 2024-02-09 CN disclosed
CN-114874361-B Iodine-controlled reversible-deactivated free radical polymerization catalytic polymerization system 苏州大学 2023-08-11 CN disclosed
US-5023341-A Acetylene thiochroman ALLERGAN, INC. (US) 1991-06-11 US disclosed
CN-1050385-A Preparation has bioactive method and the intermediate that has the compound of disubstituted acetylene moiety of retinoic acid-like ALLERGAN INC (US) 1991-04-03 CN disclosed
EP-0419132-A2 Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity ALLERGAN, INC. (US) 1991-03-27 EP disclosed
EP-0419131-A2 Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity ALLERGAN, INC. (US) 1991-03-27 EP disclosed
US-4980369-A ANTIARTHRITIC AGENTS, SKIN DISORDERS, ANTIULCER AGENTS, WOUND HEALING AGENTS ALLERGAN, INC. (US) 1990-12-25 US disclosed
US-4810804-A PSORIASIS ALLERGAN, INC. (US) 1989-03-07 US disclosed
EP-0290130-A1 Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid like activity ALLERGAN, INC (US) 1988-11-09 EP disclosed