Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.55 |
| ▸ | F13A1 | P00488 | 8/20 | 0.55 |
| ▸ | TGM1 | P22735 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738205 | 0.91 | TGM2 (0.55) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL5738625 | 0.86 | TGM2 (0.56) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL1684972 | 0.84 | TGM2 (0.69) | TGM2F13A1TGM1SMN1; SMN2POLB | |
| SCHEMBL2376710 | 0.83 | ABL1 (0.59) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL4889878 | 0.83 | MEN1 (0.76) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL18410584 | 0.82 | TGM2 (0.65) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL5424584 | 0.82 | PKLR (0.56) | TGM2F13A1TGM1 | |
| SCHEMBL3210642 | 0.81 | TGM2 (0.59) | TGM2F13A1TGM1MEN1KMT2A | |
| SCHEMBL27200534 | 0.81 | TGM2 (0.64) | TGM2F13A1TGM1SMN1; SMN2POLB | |
| SCHEMBL25085726 | 0.81 | TGM2 (0.64) | TGM2F13A1TGM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008145-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |