SCHEMBL530169

SCHEMBL530169

O=C(NC1CCCCC1)Oc1cccc(-c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 1.00
LHCGR P22888 1/20 0.80
ALDH1A1 P00352 1/20 0.76
RAB9A P51151 1/20 0.76
TRPA1 O75762 1/20 0.75
EPHX2 P34913 1/20 0.75
FAAH2 Q6GMR7 1/20 0.75
MGLL Q99685 1/20 0.75
HDAC6 Q9UBN7 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393643 1.00 FAAH (1.00) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089418 0.99 FAAH (0.97) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089399 0.93 FAAH (0.88) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089404 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089402 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089406 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089403 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089425 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089426 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089400 0.87 FAAH (0.84) FAAHTRPA1EPHX2FAAH2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085674-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ULCERATIVE COLITIS BACAINN THERAPEUTICS, INC. (US) 2025-04-24 WO disclosed
EP-2598477-B1 PERIPHERALLY RESTRICTED FAAH INHIBITORS UNIV CALIFORNIA (US) 2016-03-02 EP disclosed
US-9187413-B2 Peripherally restricted FAAH inhibitors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-11-17 US disclosed
EP-1558591-B1 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS UNIV CALIFORNIA (US) 2014-05-07 EP disclosed
US-20130217764-A1 PERIPHERALLY RESTRICTED FAAH INHIBITORS UNIVERSITA DEGLI STUDI DI URBINO (IT) 2013-08-22 US disclosed
US-8476043-B2 Inhibitors for the soluble epoxide hydrolase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-02 US disclosed
US-8476043-B2 Inhibitors for the soluble epoxide hydrolase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-02 US disclosed
EP-2598477-A2 PERIPHERALLY RESTRICTED FAAH INHIBITORS The Regents of the University of California (US) 2013-06-05 EP disclosed
WO-2012015704-A2 PERIPHERALLY RESTRICTED FAAH INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-02-02 WO disclosed
US-20120010283-A1 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-01-12 US disclosed
US-20080103209-A1 Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-05-01 US disclosed
EP-1558591-A4 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS UNIV CALIFORNIA (US) 2007-09-12 EP disclosed
US-7176201-B2 Modulation of anxiety through blockade of anandamide hydrolysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-02-13 US disclosed
US-7176201-B2 Modulation of anxiety through blockade of anandamide hydrolysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-02-13 US disclosed
US-7176201-B2 Modulation of anxiety through blockade of anandamide hydrolysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-02-13 US disclosed
EP-1742626-A2 COMPOUNDS AND METHODS FOR TREATING NON-INFLAMMATORY PAIN USING PPARALPHA AGONISTS The Regents of The University of California (US) 2007-01-17 EP disclosed
WO-2005115370-A2 COMPOUNDS AND METHODS FOR TREATING NON-INFLAMMATORY PAIN USING PPARALPHA AGONISTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-08 WO disclosed
EP-1558591-A2 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS The Regents of the University of California (US) 2005-08-03 EP disclosed
US-20040127518-A1 Modulation of anxiety through blockade of anandamide hydrolysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-07-01 US disclosed
WO-2004033422-A2 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217764-A1 PERIPHERALLY RESTRICTED FAAH INHIBITORS FAAH, FAAH2, CNR2 FAAH 1/4885LHCGR 2543/4885ALDH1A1 623/4885
US-20080103209-A1 Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists FAAH, CNR2, FAAH2 FAAH 1/4885LHCGR 1710/4885ALDH1A1 967/4885
US-20120010283-A1 MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS FAAH, FAAH2, CNR2 FAAH 1/4885LHCGR 1617/4885ALDH1A1 734/4885
US-20040127518-A1 Modulation of anxiety through blockade of anandamide hydrolysis FAAH, FAAH2, CNR2 FAAH 1/4885LHCGR 1910/4885ALDH1A1 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.