SCHEMBL29393643

SCHEMBL29393643

O=C(NC1CCCCC1)Oc1cccc(-c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 1.00
LHCGR P22888 1/20 0.80
ALDH1A1 P00352 1/20 0.76
RAB9A P51151 1/20 0.76
TRPA1 O75762 1/20 0.75
EPHX2 P34913 1/20 0.75
FAAH2 Q6GMR7 1/20 0.75
MGLL Q99685 1/20 0.75
HDAC6 Q9UBN7 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL530169 1.00 FAAH (1.00) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089418 0.99 FAAH (0.97) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089399 0.93 FAAH (0.88) FAAHLHCGRALDH1A1RAB9ATRPA1
SCHEMBL10089404 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089402 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089406 0.90 FAAH (0.81) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089403 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089425 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089426 0.88 FAAH (0.79) FAAHTRPA1EPHX2FAAH2MGLL
SCHEMBL10089400 0.87 FAAH (0.84) FAAHTRPA1EPHX2FAAH2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US disclosed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 US disclosed
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 US disclosed
US-20250205175-A1 Anti-Aging Composition with mTOR inhibitor for Humans and Other Mammals POSTREL RICHARD (US) 2025-06-26 US disclosed
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-06-05 US disclosed
US-20250152562-A1 Compositions to Enhance and Extend Quality of Life POSTREL RICHARD (US) 2025-05-15 US disclosed
WO-2025085674-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ULCERATIVE COLITIS BACAINN THERAPEUTICS, INC. (US) 2025-04-24 WO disclosed
US-12280019-B2 Anti-aging therapy for humans and other mammals POSTREL RICHARD (US) 2025-04-22 US disclosed
US-12252556-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-03-18 US disclosed
WO-2022225839-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN THERAPEUTICS, INC. (US) 2022-10-27 WO disclosed
EP-3449943-B1 A PHARMACEUTICAL COMPOSITION FOR IMPROVING OR PREVENTING PROGRESSION OF CHRONIC KIDNEY DISEASE FRIMLINE PRIVATE LTD (IN) 2022-08-31 EP disclosed
US-20220265646-A1 PIEZO AGONISTS FOR PREVENTING OR REVERTING ABNORMAL AMYLOID DEPOSITION ITÄ-SUOMEN YLIOPISTO (FI) 2022-08-25 US disclosed
US-20220249434-A1 Reversal of Baldness in Men and Women through Cannabinoid Receptor Activation POSTREL RICHARD (US) 2022-08-11 US disclosed
US-20220175694-A1 Anti-Aging Therapy for Canines and Other Domesticated Animals POSTREL RICHARD (US) 2022-06-09 US disclosed
EP-3996702-A1 PIEZO AGONISTS FOR PREVENTING OR REVERTING ABNORMAL AMYLOID DEPOSITION Itä-Suomen Yliopisto (FI) 2022-05-18 EP disclosed
US-11331300-B2 Reversing baldness through follicle regeneration POSTREL RICHARD (US) 2022-05-17 US disclosed
US-11318093-B2 Dental topical anesthetic gel PAC-DENT, INC. 2022-05-03 US disclosed
US-11274158-B2 Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-03-15 US disclosed
CN-114126617-A Piezoelectric agonists for preventing or reversing abnormal amyloid deposition 东芬兰大学 2022-03-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252556-B2 Cyclosporine compositions and methods of use FPR2, FPR1, FPR3 FAAH 1629/4885LHCGR 3696/4885ALDH1A1 3535/4885
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE ABCC1, SLC47A2, ABCB1 FAAH 2184/4885LHCGR 4015/4885ALDH1A1 3772/4885
US-12421281-B2 Cyclosporine compositions and methods of use FPR2, FPR1, FPR3 FAAH 2000/4885LHCGR 3882/4885ALDH1A1 4140/4885
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL FAAH 12/4885LHCGR 4239/4885ALDH1A1 530/4885
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE FPR2, FPR1, FPR3 FAAH 1629/4885LHCGR 3696/4885ALDH1A1 3535/4885
US-20220265646-A1 PIEZO AGONISTS FOR PREVENTING OR REVERTING ABNORMAL AMYLOID DEPOSITION PIEZO1, STIM2, ADRA1D FAAH 2921/4885LHCGR 4671/4885ALDH1A1 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.