SCHEMBL530237

SCHEMBL530237

CC(=O)Oc1cc(S(C)(=O)=O)c(C=O)o1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.31
PTGS2 P35354 1/20 0.31
MAPT P10636 3/20 0.31
KDM4E B2RXH2 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GLA P06280 2/20 0.31
GAA P10253 2/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
ALPG P10696 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP3A4 P08684 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1249501 0.77 KDM4E (0.41) MAPTKDM4ESMN1; SMN2ALDH1A1GLA
SCHEMBL2566413 0.73 KDM4E (0.31) KDM4EALDH1A1PKM
SCHEMBL27827201 0.65 POLB (0.39) CA2PTGS2MAPTKDM4ESMN1; SMN2
SCHEMBL27748316 0.60 KDM4E (0.43) MAPTKDM4ESMN1; SMN2ALDH1A1GLA
SCHEMBL6535328 0.59 PTGS2 (0.52) PTGS2MAPTKDM4EALDH1A1GAA
SCHEMBL6254745 0.59
SCHEMBL15778442 0.58 ALDH1A1 (0.49) MAPTKDM4ESMN1; SMN2ALDH1A1GAA
SCHEMBL1260078 0.58 MAPT (0.47) CA2PTGS2MAPTKDM4ESMN1; SMN2
SCHEMBL14655825 0.58 PTGS2 (0.50) PTGS2MAPTKDM4EALDH1A1GAA
SCHEMBL28032307 0.58 KDM4E (0.38) MAPTKDM4ESMN1; SMN2ALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598466-A1 MICROWAVE ASSISTED SYNTHESIS OF DEHYDRATED SUGAR DERIVATIVES HYDROXYMETHYLFURFURAL, LEVULINIC ACID, ANHYDROSUGAR ALCOHOLS, AND ETHERS THEREOF Archer-Daniels-Midland Company (US) 2013-06-05 EP disclosed
WO-2012015616-A1 MICROWAVE ASSISTED SYNTHESIS OF DEHYDRATED SUGAR DERIVATIVES HYDROXYMETHYLFURFURAL, LEVULINIC ACID, ANHYDROSUGAR ALCOHOLS, AND ETHERS THEREOF ARCHER DANIELS MIDLAND COMPANY (US) 2012-02-02 WO disclosed