Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043320 | 0.82 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL222908 | 0.82 | NR4A1 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27356901 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| Acridine SCHEMBL29774329 | 0.80 | NR4A1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8377331 | 0.80 | ALDH1A1 (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5352931 | 0.80 | ALDH1A1 (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Water SCHEMBL7769203 | 0.80 | NR4A1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Acridine SCHEMBL31147690 | 0.80 | NR4A1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8850857 | 0.80 | NR4A1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9083721 | 0.80 | NR4A1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988068-B1 | MEDICAL DEVICES CONTAINING SEGMENTED POLYURETHANE BIOMATERIALS | MEDTRONIC INC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-6915168-B1 | Medical devices containing segmented polyurethane biomaterials | MEDTRONIC, INC. | 2005-07-05 | — | — | US | disclosed |
| EP-0988068-A2 | MEDICAL DEVICES CONTAINING SEGMENTED POLYURETHANE BIOMATERIALS | Medtronic Inc. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998050086-A2 | MEDICAL DEVICES CONTAINING SEGMENTED POLYURETHANE BIOMATERIALS | MEDTRONIC, INC. (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5198526-A | Heterocycle oligomers with multidimensional morphology | THE BOEING COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| US-5126410-A | Solvent resistant polybenzoxazoles, polybenzothiazoles and polybenzimidazoles | THE BOEING COMPANY (US) | 1992-06-30 | — | — | US | disclosed |
| US-5120819-A | Heat and sovent-resistant polybenzoxazoles,-thiazoles and -imidazoles for aerospace applications | BOEING COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-5082905-A | Blended heterocycles | THE BOEING COMPANY (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0261575-B1 | SOLVENT RESISTANT POLYETHERAMIDEIMIDES | GENERAL ELECTRIC COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4965336-A | PHENYLIMIDE ACID HALIDE ENCAPPED POLYBENZOXAZLES; CURABLE, SOLVENT RESISTANCE PREPREGS | THE BOEING COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0309649-A2 | High performance heterocycle oligomers and blends | THE BOEING COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4794153-A | Polyanhydride-siloxanes and polyimide-siloxanes obtained therefrom | GENERAL ELECTRIC COMPANY (US) | 1988-12-27 | — | — | US | disclosed |
| US-4742150-A | INJECTION MOLDABLE THERMOPLASTIC | GENERAL ELECTRIC COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0261575-A1 | Solvent resistant polyetheramideimides | GENERAL ELECTRIC COMPANY (US) | 1988-03-30 | — | — | EP | disclosed |
| US-4544503-A | REACTING HYDROXY BENZENESULFONATE WITH CARBON MONOXIDE AND OLEFIN | ETHYL CORPORATION (US) | 1985-10-01 | — | — | US | disclosed |
| US-3975345-A | ELECTROCOATING | GENERAL ELECTRIC COMPANY (US) | 1976-08-17 | — | — | US | disclosed |