Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187428 | 0.90 | PGR (0.64) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL7364604 | 0.88 | CA12 (0.59) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL95649 | 0.86 | SLC22A12 (0.55) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL18546034 | 0.84 | CYP19A1 (0.73) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL8752398 | 0.84 | ALDH1A1 (0.68) | LMNAMEN1ALOX12KMT2ASMN1; SMN2 | |
| SCHEMBL18530465 | 0.84 | SMN1; SMN2 (0.79) | LMNAMEN1ALOX12KMT2ASMN1; SMN2 | |
| SCHEMBL28750145 | 0.83 | PGR (0.56) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL4067674 | 0.83 | PGR (0.56) | LMNAMEN1ALOX12KMT2ACYP19A1 | |
| SCHEMBL13265822 | 0.80 | LMNA (0.58) | LMNAMEN1ALOX12KMT2ASMN1; SMN2 | |
| SCHEMBL8752480 | 0.80 | PGR (0.74) | LMNAMEN1ALOX12KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014273-A2 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-02-01 | — | — | WO | disclosed |