Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | CLK2 | P49760 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007934 | 0.89 | NUDT1 (0.54) | KDM4EALDH1A1POLBGAAHRH4 | |
| SCHEMBL30417616 | 0.89 | NUDT1 (0.54) | KDM4EALDH1A1POLBGAAHRH4 | |
| SCHEMBL11252790 | 0.88 | HRH4 (0.45) | ALDH1A1POLBHRH4HRH3HCAR3 | |
| SCHEMBL30639140 | 0.88 | HRH4 (0.45) | ALDH1A1POLBHRH4HRH3HCAR3 | |
| SCHEMBL2028729 | 0.82 | HRH3 (0.42) | HRH4HRH3HCAR3PTGS1PRKD3 | |
| Hydrochloric Acid SCHEMBL5694428 | 0.81 | HRH3 (0.41) | HRH4HRH3HCAR3PTGS1PRKD3 | |
| SCHEMBL29618390 | 0.81 | HCAR3 (0.56) | ALDH1A1HRH4HRH3HCAR3PTGS1 | |
| SCHEMBL2911978 | 0.81 | HCAR3 (0.56) | ALDH1A1HRH4HRH3HCAR3PTGS1 | |
| SCHEMBL7353325 | 0.81 | APP (0.42) | HRH4HRH3HCAR3PTGS1FTO | |
| SCHEMBL11264344 | 0.79 | PTGS1 (0.40) | HRH4HRH3HCAR3PTGS1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2024-12-26 | — | — | US | claimed |
| EP-4408376-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | Kao Corporation (JP) | 2024-08-07 | — | — | EP | claimed |
| CN-118043022-A | Composition comprising a dye and an inorganic alkalizing agent | 花王株式会社 | 2024-05-14 | — | — | CN | claimed |
| WO-2023054558-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2023-04-06 | — | — | WO | claimed |
| EP-4159184-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | Kao Corporation (JP) | 2023-04-05 | — | — | EP | claimed |
| EP-1963313-B1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE (DGAT) | MADRIGAL PHARMACEUTICALS INC (US) | 2012-11-14 | — | — | EP | claimed |
| EP-1963313-A2 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE (DGAT) | F.HOFFMANN-LA ROCHE AG (CH) | 2008-09-03 | — | — | EP | claimed |
| WO-2007060140-A2 | INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE (DGAT) | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-31 | — | — | WO | claimed |
| EP-1250912-B1 | Hair dye composition | KPSS KAO GMBH (DE) | 2004-09-15 | — | — | EP | claimed |
| EP-1297818-A2 | Hair dye | KPSS-Kao Professional Salon Services GmbH (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-1250912-A1 | Hair dye composition | GOLDWELL GmbH (DE) | 2002-10-23 | — | — | EP | claimed |
| US-5180399-A | Kits for dyeing hair | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| US-4588410-A | DEVELOPERS, COUPLERS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | claimed |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2024-12-26 | — | — | US | disclosed |
| CN-118804737-A | Dyeing composition in aqueous alcohol medium | 花王株式会社 | 2024-10-18 | — | — | CN | disclosed |
| EP-4408376-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | Kao Corporation (JP) | 2024-08-07 | — | — | EP | disclosed |
| US-4950302-A | Process for the production of 2,5-diamino-6-nitro-pyridine derivatives, their use in hair dye compositions and new 2,5-diamino-6-nitropyridine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | disclosed |
| EP-0303878-A2 | 2,5-diamino-nitro-6-pyridine derivatives containing hair dyeing agents | Wella Aktiengesellschaft (DE) | 1989-02-22 | — | — | EP | disclosed |
| EP-0257399-A2 | Hair dyeing composition | Beratungslabor für die kosmetische und pharmazeutische Industrie Dipl.-Ing. Karlheinz Schrader (DE) | 1988-03-02 | — | — | EP | disclosed |
| US-4588410-A | DEVELOPERS, COUPLERS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KRT18, COL14A1, COL1A1 | KDM4E 1590/4885ALDH1A1 2007/4885POLB 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.