Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.76 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296892 | 0.92 | HCAR2 (0.67) | HCAR2LTB4RRAB9AHSD17B1SLC13A5 | |
| SCHEMBL5301209 | 0.89 | HCAR2 (0.59) | HCAR2LTB4R | |
| SCHEMBL14340801 | 0.86 | HCAR2 (1.00) | HCAR2LTB4RRAB9A | |
| SCHEMBL5062205 | 0.86 | HCAR2 (0.64) | HCAR2LTB4R | |
| SCHEMBL3558904 | 0.84 | HCAR2 (0.56) | HCAR2RAB9A | |
| SCHEMBL14609697 | 0.84 | HCAR2 (0.58) | HCAR2LTB4R | |
| SCHEMBL5299672 | 0.83 | HCAR2 (0.53) | HCAR2LTB4R | |
| SCHEMBL5306464 | 0.82 | HCAR2 (0.55) | HCAR2LTB4RMME | |
| SCHEMBL5061223 | 0.82 | KDM4E (0.62) | HCAR2LTB4RRAB9A | |
| SCHEMBL5300760 | 0.81 | ALDH1A1 (0.56) | HCAR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |