Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 9/20 | 0.50 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309091 | 0.90 | SCD (0.60) | DCTPP1SCD | |
| SCHEMBL5311547 | 0.85 | LMNA (0.46) | PRKAA2ALDH1A1LMNA | |
| SCHEMBL5370515 | 0.84 | DCTPP1 (0.46) | DCTPP1SCDCYP1A2CYP2C19KMT2A | |
| SCHEMBL5306130 | 0.84 | DCTPP1 (0.49) | DCTPP1SCDPRKAA2KMT2A | |
| SCHEMBL5309746 | 0.83 | SCD (0.68) | DCTPP1SCD | |
| SCHEMBL5358417 | 0.83 | SCD (0.60) | DCTPP1SCD | |
| SCHEMBL5312775 | 0.82 | SCD (0.59) | DCTPP1SCD | |
| SCHEMBL5493321 | 0.82 | DCTPP1 (0.44) | DCTPP1SCDALDH1A1KMT2A | |
| SCHEMBL5309412 | 0.81 | SCD (0.55) | DCTPP1SCD | |
| SCHEMBL5309658 | 0.80 | DCTPP1 (0.41) | DCTPP1SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |