Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306200 | 0.85 | DCTPP1 (0.50) | LMNAPRKAA2ALDH1A1 | |
| SCHEMBL5311551 | 0.84 | PRKAA2 (0.43) | LMNAPRKAA2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5309649 | 0.83 | SCD (0.57) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL5307062 | 0.83 | SCD (0.51) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL5314065 | 0.82 | ALDH1A1 (0.44) | LMNASMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5312604 | 0.82 | SCD (0.41) | LMNASMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5314055 | 0.81 | SMN1; SMN2 (0.51) | PRKAA2SMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL5307475 | 0.81 | CA2 (0.41) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL5312323 | 0.80 | SCD (0.48) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL5309151 | 0.77 | SCD (0.45) | SMN1; SMN2ALDH1A1KDM4EMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |