Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 11/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315061 | 0.89 | SCD (0.45) | SMN1; SMN2TDP1RAB9ANPC1F10 | |
| SCHEMBL5311766 | 0.84 | F10 (0.47) | SMN1; SMN2TDP1RAB9ANPC1TSHR | |
| SCHEMBL5310358 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1RAB9ANPC1TSHR | |
| SCHEMBL5307546 | 0.81 | SCD (0.45) | SMN1; SMN2RAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL5307322 | 0.80 | SCD (0.54) | SMN1; SMN2RAB9AALDH1A1HTT | |
| SCHEMBL5312064 | 0.79 | SCD (0.43) | CRACR2A | |
| SCHEMBL5310356 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1RAB9ANPC1TSHR | |
| SCHEMBL5309113 | 0.78 | SCD (0.47) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5306277 | 0.77 | FAAH (0.37) | SMN1; SMN2ALDH1A1KMT2ACRACR2AHTT | |
| SCHEMBL5312273 | 0.77 | KCNQ3 (0.44) | SMN1; SMN2RAB9AALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |