Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303090 | 0.88 | MAPT (0.51) | TP53MAPTACP1ALDH1A1HSD17B10 | |
| SCHEMBL5310087 | 0.87 | CYP1A2 (0.44) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL5332325 | 0.85 | MAPT (0.45) | TP53MAPTPOLBGAACLK4 | |
| SCHEMBL5306559 | 0.84 | KDM4E (0.47) | TP53MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5304392 | 0.82 | CYP1A2 (0.45) | TP53MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL5303639 | 0.81 | LMNA (0.44) | TP53MAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5306913 | 0.80 | CDK2 (0.40) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL5307225 | 0.80 | MAPT (0.48) | TP53MAPTACP1ALDH1A1HSD17B10 | |
| SCHEMBL5306328 | 0.79 | F2 (0.47) | TP53MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5304358 | 0.79 | MAPT (0.45) | TP53MAPTPOLBCLK4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |