Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303090 | 0.87 | MAPT (0.51) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL10119764 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL5303639 | 0.84 | LMNA (0.44) | KDM4EALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL5306369 | 0.84 | TP53 (0.48) | KDM4EALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL5307225 | 0.83 | MAPT (0.48) | KDM4EALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL5304358 | 0.82 | MAPT (0.45) | KMT2AMAPTTDP1L3MBTL1POLB | |
| SCHEMBL5306328 | 0.82 | F2 (0.47) | KDM4EALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL5310087 | 0.81 | CYP1A2 (0.44) | KDM4EALDH1A1KMT2AMAPTTDP1 | |
| SCHEMBL5304392 | 0.81 | CYP1A2 (0.45) | ALDH1A1KMT2AMAPTLMNAHPGD | |
| SCHEMBL5306913 | 0.81 | CDK2 (0.40) | KDM4EALDH1A1MAPTTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034279-A2 | C3A ANTAGONISTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |