Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767130 | 0.81 | NPC1 (0.42) | ABL1ABCB1BCRALDH1A3ALDH1A1 | |
| SCHEMBL732632 | 0.81 | CYP1A1 (0.45) | ABL1ABCB1BCRALDH1A1MAPT | |
| SCHEMBL28916864 | 0.78 | AHR (0.46) | HPGDALDH1A1MAPTAHRTP53 | |
| SCHEMBL9254 | 0.78 | — | — | |
| SCHEMBL19693022 | 0.77 | MAOB (0.50) | ABL1ABCB1BCR | |
| SCHEMBL3947663 | 0.75 | HPGD (0.59) | ABL1ABCB1BCRHPGDRAB9A | |
| SCHEMBL11676999 | 0.75 | AHR (0.40) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL792192 | 0.73 | CNR1 (0.59) | ABL1ABCB1BCRALDH1A3CNR1 | |
| SCHEMBL21647914 | 0.72 | CYP1A2 (0.65) | ALDH1A3ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL63193 | 0.72 | ALDH1A1 (0.59) | ABL1ABCB1BCRALDH1A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019397-A2 | 6-MEMBERED ARYL AND HETEROARYL DERIVATIVES FOR THE TREATMENT OF HEPATITIS C VIRUS | GENELABS TECHNOLOGIES, INC. (US) | 2007-02-15 | — | — | WO | claimed |
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2007019397-A2 | 6-MEMBERED ARYL AND HETEROARYL DERIVATIVES FOR THE TREATMENT OF HEPATITIS C VIRUS | GENELABS TECHNOLOGIES, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | HAVCR2, MAVS, EIF2AK2 | ABL1 42/4885ABCB1 838/4885BCR 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.